Modify Search
Select all
Products
Pages
Posts
Modify Search
Select all
Products
Pages
Posts

Ambroxol HCl | Free radical scavenger

CAS:
18683-91-5
Catalog Number:
10-2296
Activity:
Free radical scavenger
Chemical Name:
trans-4-(2-Amino-3,5-dibromobenzylamin)cyclohexane _ HCl
Molecular Weight:
414.56
Molecular Formula:
C13H18Br2N2O HCl
Solubility:
Soluble in Water.
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
Shipping Code:
RT

Ambroxol HCl (18683-91-5) is a radical scavenger with anti-inflammatory activity. Blocks the generation of reactive oxygen species by bronchoalveolar lavage cells, inhibits doxorubicin-induced lipid peroxidation (70 mg/kg in rat), and inhibits the release of inflammatory mediators from human leukocytes and mast cells (effective dose ~ 100 μM)

References/Citations:

1) Teramoto et al. (1999), Effects of ambroxol on spontaneous or stimulated generation of reactive oxygen species by bronchoalveolar lavage cells harvested from patients with or without chronic obstructive pulmonary diseases; Pharmacology, 59 135
2) Nowak et al. (1995), Ambroxol inhibits doxorubicin-induced lipid peroxidation in heart of mice; Free Radic. Biol. Med., 19 659
3) Gibbs et al. (1999), Ambroxol inhibits the release of histamine, leukotrienes and cytokines from human leukocytes and mast cells; Inflamm. Res., 48 86

Ambroxol HCl | Free radical scavenger is also available in the Cellular Metabolism Library.
CAS:
18683-91-5
Catalog Number:
10-2296
Activity:
Free radical scavenger
Chemical Name:
trans-4-(2-Amino-3,5-dibromobenzylamin)cyclohexane _ HCl
Molecular Weight:
414.56
Molecular Formula:
C13H18Br2N2O HCl
Solubility:
Soluble in Water.
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Add to Quote

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee