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BAPTA-free acid | Extracellular calcium sponge

CAS:
85233-19-8
Catalog Number:
10-1204
Activity:
Extracellular calcium sponge
Chemical Name:
1,2-bis-(2-Aminophenoxy)ethane-N,N,N’,N,-tetraacetic acid
Molecular Weight:
476.43
Molecular Formula:
C22H24N2O10
Solubility:
Soluble in DMSO (up to 20 mg/ml)
Physical Properties:
White solid
Purity:
97% by HPLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT

BAPTA free acid (85233-19-8) is a selective extracellular Ca2+ chelator. It is a widely used calcium sponge for chelating Ca2+ outside of intact cells.1 It’s a useful tool to probe the involvement of extracellular Ca2+ in cellular signaling.2,3 Non-cell-permeable.

References/Citations:

1) Munoz et al. (2015), Different Stress-Induced Calcium Signatures Are Reported by Aequorin-Mediated Calcium Measurements in Living Cells of Aspergillus fumigatus; PLoS One, 10(9) e0138008
2) Wozniak et al. (2017), Extracellular Ca2+ is Required for Fertilization in the African Clawed Frog, Xenopus laevis; PLoS One, 12(1) e0170405
3) Didiasova et al. (2015), STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization; J. Biol. Chem., 290 11983

BAPTA-free acid | Extracellular calcium sponge is also available in the Cellular Metabolism Library.
CAS:
85233-19-8
Catalog Number:
10-1204
Activity:
Extracellular calcium sponge
Chemical Name:
1,2-bis-(2-Aminophenoxy)ethane-N,N,N’,N,-tetraacetic acid
Molecular Weight:
476.43
Molecular Formula:
C22H24N2O10
Solubility:
Soluble in DMSO (up to 20 mg/ml)
Physical Properties:
White solid
Purity:
97% by HPLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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