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Product Details

CAPE | Inhibits NFkB activation

CAPE (104594-70-9) is an antioxidant that inhibits NFκB activation and the growth of transformed cells. CAPE inhibits lipid peroxidation and displays antiinflammatory activity. Cell permeable.

References/Citations
1) Sudine et al. (1993) Caffeic scid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties. FEBS Lett. 21 329
2) Natarajan et al. (1996) Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B. Proc. Natl. Acad. Sci. USA 93 9090
3) Chiao et al. (1995). Apoptosis and altered redox state induced by caffeic acid phenethyl ester (CAPE) in transformed rat fibroblast cells; Cancer Res. 55 3576
4) Orban et.al. (2000), Caffeic acid phenethyl ester induces leukocyte apoptosis, modulates nuclear factor-kappa B and suppresses acute inflammation; Neuroimmunimodulation, 7 99

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Catalog#  10-2265

$30.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
104594-70-9
Catalog Number:
10-2265
Activity:
Inhibits NFκB activation
Alternate Names:
Caffeic acid phenethylester
Chemical Name:
3-(3,4-Dihydroxyphenyl)-2-propenoic acid 2-phenylethyl ester
Molecular Weight:
284.32
Molecular Formula:
C17H16O4
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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