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Lipid Metabolism

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  • GE-501516 | PPAR delta agonist
    $68.00
    GW-501516 (317318-70-0) is a potent and selective PPARδ (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes.1  Induces apolipoprotein A1-mediated cholesterol efflux in vitro.1 Improves...

  • GSK-3787 | 188591-46-0 | Supplier | Structure
    $60.00
    GSK-3787 (188591-46-0) is a selective and irreversible antagonist of the peroxisome proliferator-activated receptor delta (PPARδ) plC50 = 6.6. It covalently binds to Cys 249 in the PPARδ binding site...

  • Lovastatin | 75330-75-5 | Structure | Supplier
    $41.00
    Lovastatin (75330-75-5) Blocks cholesterol and isoprenoid biosynthesis via inhibition of HMG-CoA reductase (Ki=1nM for acid form).1,2 Induces apoptosis in various cell lines.3 Causes cell cycle arrest in early G1 phase.4...

  • Simvastatin | 79902-63-9 | Structure | Supplier
    $30.00
    Simvastatin (79902-63-9) is a synthetic analog of lovastatin (cat.# 10-1222). Blocks cholesterol and isoprenoid biosynthesis via inhibition of HMG-CoA reductase1,2. Simvastatin induces apoptosis in various cell lines and...

  • SR-144528 | 192703-06-3 | Structure | Supplier
    $100.00
    SR-144528 (192703-06-3) is a potent and selective antagonist of the cannabinoid CB2 receptor1,2. References/Citations1) Rinaldi-Carmona et al. (1998), SR-144528, the first potent and selective antagonist of the CB2...

  • TMP-153 | ACAT inhibitor
    $36.00
    TMP-153 (128831-46-9) is a potent and selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), IC50=5-10 nM. It inhibits cholesterol absorption and lowers plasma cholesterol in rats and hamsters.1,2 TMP-153...

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