Modify Search
Select all
Products
Pages
Posts
Modify Search
Select all
Products
Pages
Posts

Carnosic acid | Antioxidant

CAS:
3650-09-7
Catalog Number:
10-2401
Activity:
antioxidant
Chemical Name:
Natural diterpenoid resorcinol isolated from Rosmarinus officinalis.
Molecular Weight:
332.42
Molecular Formula:
C20H28O4
Solubility:
Soluble in DMSO (up to 50 mg/ml).
Physical Properties:
Off-white or yellow solid
Purity:
95% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT

Carnosic acid (3650-09-7) is an antioxidant and free radical scavenger. Increases cellular levels of glutathione (GSH) and prevents 6-hydroxydopamine-induced cell death in SH-SY5Y cells.1 Carnosic acid-stimulation of GSH inhibits adipocyte differentiation.2 Induces apoptosis3 and inhibits the proliferation and migration of various tumor cell lines4.

References/Citations:

1) Chen et al. (2012), Carnosic acid prevents 6-hydroxydopamine-induced cell death in SH-SY5Y cells via mediation of glutathione synthesis; Chem. Res. Toxicol., 25 1893
2) Takahashi et al. (2009), Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase2 enzymes and activation of glutathione metabolism; Biochem. Biophys. Res. Commun., 382 549
3) Kar et al. (2012), Carnosic acid modulates Akt/IKK/NFκB signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells; Apoptosis, 17 735
4) Barni et al. (2012), Carnosic acid inhibits the proliferation and migration capacity of human colorectal cancer cells; Oncol. Rep., 27 1041

Carnosic acid | Antioxidant is also available in the Cellular Metabolism Library.
CAS:
3650-09-7
Catalog Number:
10-2401
Activity:
antioxidant
Chemical Name:
Natural diterpenoid resorcinol isolated from Rosmarinus officinalis.
Molecular Weight:
332.42
Molecular Formula:
C20H28O4
Solubility:
Soluble in DMSO (up to 50 mg/ml).
Physical Properties:
Off-white or yellow solid
Purity:
95% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Add to Quote

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee