Mitochondrial

  • A77 1726 | DHODH inhibitor

    CAS:
    108605-62-5
    Catalog Number:
    10-1436
    Activity:
    DHODH inhibitor
    Alternate Names:
    Teriflunomide
    Chemical Name:
    2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
    Molecular Weight:
    270.21
    Molecular Formula:
    C12H9F3N2O2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $45.00
  • AGI-5198 | R132 mutant isocitrate dehydrogenase inhibitor

    CAS:
    1355326-35-0
    Catalog Number:
    10-4599
    Activity:
    R132 mutant isocitrate dehydrogenase inhibitor
    Chemical Name:
    N-[2-(Cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-2-methyl-1H-imidazole-1-acetamide
    Molecular Weight:
    462.56
    Molecular Formula:
    C27H31FN4O2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
  • Antimycin A | Mitochondrial Complex III inhibitor

    Antimycin A (1397-94-0) is a mitochondrial electron transport inhibitor at complex III. Induces apoptosis in various cell lines.1 Antimycin A may be used to generate cellular models […]

    From $50.00
  • BAY 87-2243 | HIF-1 / Mitochondrial complex I inhibitor

    CAS:
    1227158-85-1
    Catalog Number:
    10-4910
    Activity:
    HIF-1 / Mitochondrial complex I inhibitor
    Chemical Name:
    5-[1-[[2-(4-Cyclopropylpiperazin-1-yl)pyridin-4-yl]methyl]-5-methylpyrazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole
    Molecular Weight:
    525.54
    Molecular Formula:
    C26H26F3N7O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $65.00
  • Brequinar sodium | Dihydroorotate dehydrogenase inhibitor, antiviral

    CAS:
    96201-88-6
    Catalog Number:
    10-3965
    Activity:
    Dihydroorotate dehydrogenase inhibitor, antiviral
    Chemical Name:
    6-Fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquinoline-4-carboxylic acid sodium salt
    Alternate Name:
    DuP-785; NSC 368390
    Molecular Weight:
    397.35
    Molecular Formula:
    C23H14F2NO2•Na
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to 15 mg/ml with warming)
    Physical Properties:
    Off-white or white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20° C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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