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CVPA | Aquaporin 1 inhibitor

CAS:
37710-81-9
Catalog Number:
10-1430
Activity:
Aquaporin 1 inhibitor
Alternate Names:
3,3′-(1,3-Phenylene)bis(2-propenoic acid)
Chemical Name:
3-[3-(2-Carboxy-vinyl)-phenyl]-acrylic acid
Molecular Weight:
218.21
Molecular Formula:
C12H10O4
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
97% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of pruchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

CVPA (37710-81-9) is an aquaporin-1 inhibitor (IC50 = 8.1 μM) discovered by molecular docking against the extracellular domain of human aquaporin-1 followed by experimental testing in a Xenopus oocyte swelling assay.1

References/Citations:

1) Seeliger et al. (2012), Discovery of novel human aquaporin-1 blockers; ACS Chem. Biol., 8 249

CVPA | Aquaporin 1 inhibitor is also available in the Cellular Metabolism Library.
CAS:
37710-81-9
Catalog Number:
10-1430
Activity:
Aquaporin 1 inhibitor
Alternate Names:
3,3′-(1,3-Phenylene)bis(2-propenoic acid)
Chemical Name:
3-[3-(2-Carboxy-vinyl)-phenyl]-acrylic acid
Molecular Weight:
218.21
Molecular Formula:
C12H10O4
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
97% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of pruchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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