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Physiological Process ReagentsDiabetes

Diabetes

Focus Biomolecules offers a broad range of innovative tools for the research of diabetes.

View All Diabetes Reagents

 

Adipogenesis

  • A-769662

    A potent and reversible AMP-activated protein kinase (AMPK) allosteric activator

  • Fatostatin

    Blocks adipogenesis

View All Adipogenesis Reagents

AMPK  

  • A-769662

    A potent and reversible AMP-activated protein kinase (AMPK) allosteric activator

  • AdipoRon

    A novel potent and selective adiponectin (AdipoR1 and AdipoR2) receptor agonist

  • AICAR

    AMPK activator

  • Dorsomorphin

    AMPK inhibitor

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GSK 

  • CHIR-99021

    A potent and selective inhibitor of glycogen synthase kinase-3β (GSK3β, IC50 = 5 nM) and GSK3α (IC50 = 10 nM)

  • Indirubin-3'-monoxime

    A potent GSK-3β inhibitor (IC50=22 nM)

  • SB-216763

    A potent and selective inhibitor of glycogen synthase kinase-1 (GSK-3) IC50=34.3 nM

  • 6BIO

    A potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3) IC50=5 nM

View All GSKb Reagents

PPAR    

  • Rosiglitazone

    Agonist for the peroxisome proliferator-activated receptor gamma (PPARγ)

  • WY-14643

    A selective PPARα agonist

  • GW-9662

    A selective PPARγ antagonist

  • GSK-3787

    A selective and irreversible antagonist of the peroxisome proliferator-activated receptor delta (PPARδ) plC50 = 6.6

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