my account
Login
  Loading... Please wait...

Adipogenesis

Sort by
  • 20(S)-Hydroxycholesterol | Smoothened activator
    $45.00
    20-(S)-Hydroxycholesterol (516-72-3) is an endogenous ligand for the LXR receptor.1 It has anti-adipogenic and pro-osteogenic effects in mesenchymal stem cells mediated via a non-LXR dependent pathway.2 The osteogenic...

  • A-769662 is a potent and reversible AMP-activated protein kinase (AMPK) allosteric activator
    $72.00
    A-769662 (844499-71-4) is a potent and reversible AMP-activated protein kinase (AMPK) allosteric activator.  Activates AMPK by binding to the β and γ subunits and not the AMP binding site.1 EC50=0.8 mM for...

  • BADGE | PPAR gamma antagonist
    $30.00
    BADGE (1675-54-3) is a PPARγ antagonist with μM affinity in 3T3-L1 and 3T3-F442A preadipocyte cells. Selective over PPARδ and PPARα. Antagonizes the ability of rosiglitazone to stimulate transcriptional...

  • CHIR-99021 potent and selective inhibitor
    $70.00
    CHIR-99021 (252917-06-9) is a potent and selective inhibitor of glycogen synthase kinase-3β (GSK3β, IC50 = 5 nM) and GSK3α (IC50 = 10 nM)1. Induces osteoblastogenesis, increases mineralization and inhibits...

  • Ciglitazone | 74772-77-3 | Structure | Supplier
    $80.00
    Ciglitazone (74772-77-3) is a PPARγ agonist (EC50=3 μM). Stimulates adipogenesis in human mesenchymal stem cells. Ciglitazone inhibits HUVEC differentiation and angiogenesis. Cell permeable. References/Citations1)...

  • Fatostatin | 125256-00-0 | Structure | Supplier
    $50.00
    Fatostatin (125256-00-0) blocks adipogenesis by inhibiting the activation of SREBP. Inhibits the ER-Golgi translocation of SREBPs via binding to their escort protein (SCAP). Fatostatin prevents increases in body weight,...

  • Piceatannol | SIRT1 activator
    $45.00
    Piceatannol (10083-24-6) is a naturally occurring analog of resveratrol (Cat.# 10-1057). Inhibits nonreceptor kinases Syk and Lyk (IC50 approximately 10 μM)1. Piceatannol stimulates Sirt12. References/Citations1) Seow et...

  • SirtAct | Sirt1 activator
    $80.00
    SirtAct (839699-72-8) is a Sirt1 activator (233% at 10 μM)1 Suppresses TNFα release from THP-1 cells and stimulates adipogenesis in 3T3L1 cells1. SIRT1 stimulation by SirtAct leads to decreased tissue factor...

  • Troglitazone | 97322-87-7 | Structure | Supplier
    $86.00
    Troglitazone (97322-87-7) is a PPARγ agonist. Stimulates recruitment of transcriptional coactivators to PPARγ at 1 μM. Stimulates adipogenesis in human mesenchymal stem cells. Troglitazone induces apoptosis in...

Share Focus

Connect with Focus