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Biochemical Process ReagentsEpigenetics

Epigenetics

Epigenetic mechanisms play a role in the regulation of numerous aspects of cellular function. As such, when conditions are not related to known environmental or genetic influences they are considered of epigenetic origin.

Focus Biomolecules offers a wide range of products for epigenetic studies. Our substantial in-house development and custom synthesis capabilities make our epigenetic products one of our most popular research tools, especially in the field of cancer research. 

Call about customizations for your research needs: 610-994-1134.

View All Epigenetics Reagents

Bromodomains 

  • JQ1 (+/-)

    A Potent BET bromodomain inhibitor

  • RVX-208

    A potent BET bromodomain antagonist

View All Bromodomains

DNA Methylation

  • 5-Azacytidine

    A specific inhibitor of DNA methyltransferase

  • Decitabine

    Inhibits DNA methyltransferase

  • RG-108

    A non-nucleoside DNA methyltransferase inhibitor

  • Zebularine

    An orally active DNA methyltransferase inhibitor

View All DNA Methylation

Histone Deacetylation

  • Trichostatin A

    A potent and selective histone deacetylase (HDAC) inhibitor

  • SAHA

    A potent and selective histone deacetylase inhibitor

  • EX-527

    A selective SIRT1 inhibitor

  • Tubastatin A · HCl

    A potent and highly selective inhibitor of HDAC6
View All Histone Deacetylation

Histone Demethylation

View All Histone Demethylation

Histone Methylation

  • BIX-01294

    A selective inhibitor of G9a histone methyltransferase and GLP HMTase

  • Chaetocin

    An antimicrobial fungal metabolite

  • TC-E 5003

    A selective protein arginine methyltransferase 1 inhibitor

  • UNC1999

    A highly selective inhibitor of wild-type and mutant EZH1 and EZH2 lysine methyltransferases

View All Histone Methylation

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