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Product Details

Epothilone B | Microtubule stabilizing agent

Epothilone B (152044-54-7) induces microtubule polymerization. Causes cell cycle arrest at the G2-M transition (EC50 = 32 nM for HeLa cells). Induces apoptosis. Cell permeable.

References/Citations
1) Goodin et al. (2004), Epothilones: mechanism of action and biologic activity; J. Clin. Oncol., 22 2015
2) Bollag et al. (1995), Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action; Cancer Res., 55 2325

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Catalog#  10-2133

$85.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
152044-54-7
Catalog Number:
10-2133
Activity:
Microtubule stabilizing agent
Alternate Names:
EPO-906; EpoBI, Patupilone
Molecular Weight:
507.69
Molecular Formula:
C27H41NO6S
Solubility:
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 35 mg/ml).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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