my account
Login
  Loading... Please wait...

Product Details

Etoposide | Topoisomerase II inhibitor

Etoposide (33419-42-0) is a chemotherapeutic agent that forms a ternary complex with DNA and topoisomerase II, preventing re-ligation of DNA strands causing DNA cleavage. Etoposide blocks the cell cycle in S-phase and G2-phase.

References/Citations
1) Hande (1998) Etoposide: four decades of development of a topoisomerase II inhibitor; Eur. J. Cancer 34 1514
2) Smith et.al. (1994) Etoposide-induced cell cycle delay and arrest-dependent modulation of DNA topoisomerase II in small-cell lung cancer cells; Br. J. Cancer. 70 914

swipe
Etoposide | 33419-42-0 | Structure | Supplier

Catalog#  10-1123

$68.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
Request Bulk Quote
CAS:
33419-42-0
Catalog Number:
10-1123
Activity:
Topoisomerase II inhibitor
Chemical Name:
4_-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-_-D-glucopyranoside
Molecular Weight:
588.56
Molecular Formula:
C29H32O13
Solubility:
Soluble in DMSO (up to 30 mg/ml).
Physical Properties:
White solid
Purity:
98%
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Share Focus

Connect with Focus

Click the button below to add the Etoposide | Topoisomerase II inhibitor to your wish list.