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Protein synthesis

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  • 5-Ethynyl-2'-deoxyuridine | DNA labeling
    $50.00
    5-Ethynyl-2'-deoxyuridine (61135-33-9) is a novel agent for fast and sensitive detection of DNA synthesis in vivo1. 5-EdU is incorporated into proliferating cells followed by detection with a fluorescent azide using click...

  • Actinomycin D | Transcription inhibitor
    $57.00
    Actinomycin D (50-76-0) is a clinically useful antitumor agent. Actinomycin D has the ability to inhibit transcription by binding DNA at the transcription initiation complex and preventing elongation of RNA chain by RNA...

  • Anisomycin | Anoikis sensitizer
    $35.00
    Anisomycin (22862-76-6) activates JNK/SAPKs and reduces c-fos and c-jun. Protein synthesis inhibitor. Anisomycin induces apoptosis and sensitizes cells to anoikis. Cell permeable. References/Citations1) Hazzalin et al...

  • Blasticidin S HCl | Antibiotic selection agent
    $80.00
    Blasticidin S HCl (3513-03-9) is a peptidyl nucleoside antibiotic inhibiting protein synthesis in bacteria and eukaryotes.1 Inhibits translation by trapping deformed tRNA on the ribosome.1 The ABC-type transporter NppA1A2BCD...

  • Borrelidin | 7184-60-3 | Structure | Supplier
    $190.00
    Borrelidin (7184-60-3) is a novel macrolide which inhibits bacterial and eukaryotic threonyl-tRNA synthetase.1 Displays potent anti-angiogenic activity and induces the collapse of newly formed capillary tubules...

  • Cycloheximide | 66-81-9 | Structure | Supplier
    $35.00
    Cycloheximide (66-81-9) is a protein synthesis inhibitor. Induces apoptosis. Antifungal activity. Cell permeable. References/Citations1) Merck 14:2728

  • IPTG (animal free) | Induces beta-galactosidase in bacteria
    $25.00
    IPTG (367-93-1; animal free) induces β-galactosidase in bacteria.

  • Mithramycin A | Transcription inhibitor
    $40.00
    Mithramycin A (18378-89-7) inhibits DNA methyl transferase.1 A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibiting their expression.2...

  • Mupirocin | 12650-69-0 | Structure | Supplier
    $80.00
    Mupirocin (12650-69-0) is a topical antibiotic/antibacterial.1 It inhibits isoleucyl-tRNA synthase. High level mupirocin resistance was found in 8.2% of Staphylococcus aureus and 15.6% of coagulase-negative staphylococci...

  • Puromycin | Translation inhibitor
    $50.00
    Puromycin (58-58-2) is an aminonucleoside antibiotic derived from Streptomyces alboniger. It is a protein synthesis inhibitor that disrupts peptide transfer on ribosomes causing premature chain termination.1 It is an...

  • Thiostrepton | Antibiotic and FOXM1 inhibitor
    $85.00
    Thiostrepton (1393-48-2) is a novel cyclopeptide antibiotic. Blocks bacterial protein synthesis by inhibition of mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery as well as...

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