my account
Login
  Loading... Please wait...

Product Details

GSK-3787 | PPAR delta antagonist

GSK-3787 (188591-46-0) is a selective and irreversible antagonist of the peroxisome proliferator-activated receptor delta (PPARδ) plC50 = 6.6. It covalently binds to Cys 249 in the PPARδ binding site.

References/Citations
1) Shearer et al., (2010) Identification and characterization of 4-chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist; J. Med. Chem., 53 1857
2) Palkar et al. (2010) Cellular and pharmacological selectivity of the peroxisone proliferator-activated receptorδ antagonist GSK3787; Mol. Pharmacol. 78 419

swipe
GSK-3787 | 188591-46-0 | Supplier | Structure

Catalog#  10-1001

$60.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
Request Bulk Quote
CAS:
188591-46-0
Catalog Number:
10-1001
Activity:
PPARδ antagonist
Chemical Name:
4-Chloro-N-(2-{[5-(trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide
Molecular Weight:
392.78
Molecular Formula:
C15H12ClF3N2O3S
Solubility:
Soluble in DMSO (up to 30 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Share Focus

Connect with Focus

Click the button below to add the GSK-3787 | PPAR delta antagonist to your wish list.