GTPase
GTPases are enzymes that hydrolize GTP to GDP. They include elongation factors, G proteins (which interact with GPCRs, large GTPases, and tubulin. Some use accessory proteins to assist in their signaling functions.
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6-Mercaptopurine | Purine antimetabolite and immunomodulator
From $25.00CAS:6112-76-1Catalog Number:10-4698Activity:Purine antimetabolite and immunomodulatorChemical Names:3,7-Dihydropurine-6-thione monohydrateAlternate Name:6-MPMolecular Weight:170.19Molecular Formula:C5H4N4S·H2OSolubility:Soluble in DMSO (>50 mg/ml); ethanol (5 mg/ml with warming)Physical Properties:Yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:Room temperatureStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
AMG 510 |Covalent KRASG12C Inhibitor
From $69.00AMG 510 (2296729-00-3; Sotorasib) is a potent (IC50’s = 6 nM NCI-H358; 9 nM MIA PaCa-2) covalent KRASG12C inhibitor.1,2 It significantly inhibited tumor growth in NCI-H358 and MIA […]
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CCG-4986 | RGS4 inhibitor
From $60.00CAS:7134-19-2Catalog Number:10-1431Activity:RGS4 inhibitorChemical Names:Methyl-N-[(4-chlorophenyl)sulfonyl]-4-nitrobenzenesulfinimidoateMolecular Weight:374.81Molecular Formula:C13H11ClN2O5S2Solubility:Soluble in DMSO (60 mg/ml); Ethanol (5 mg/ml with warming)Physical Properties:White solidPurity:>98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
CID1067700 | Rab7 GTPase inhibitor
From $65.00CAS:314042-01-8Catalog Number:10-5401Activity:Rab7 GTPase inhibitorChemical Name:2-[[(Benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid; ML282
Molecular Weight:390.48Molecular Formula:C18H18N2O4S2Solubility:Soluble in DMSO (up to 40 mg/ml)Physical Properties:White solidPurity:98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Dynasore | Dynamin inhibitor
From $45.00CAS:304448-55-3Catalog Number:10-1427Activity:Dynamin inhibitorChemical Name:3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazideMolecular Weight:322.32Molecular Formula:C18H14N2O4Solubility:Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 1 mg/ml).Physical Properties:Beige solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
MBQ-167 | Dual Rac/Cdc42 inhibitor
From $75.00CAS:2097938-73-1Catalog Number:10-4434Activity:Dual Rac/Cdc42 inhibitorChemical Names:1-(9-Ethyl-9H-carbazol-3-yl)-5-phenyl-1H-1,2,3-triazoleMolecular Weight:338.41Molecular Formula:C22H18N4Solubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT
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