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ID-8 | DYRK Inhibitor

CAS:
147591-46-6
Catalog Number:
10-4506
Activity:
DYRK Inhibitor
Chemical Name:
1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol
Molecular Weight:
298.29
Molecular Formula:
C16H14N2O4
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
Solid
Purity:
99%
NMR (Confirms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

ID-8 (147591-46-6) enhances stem cell proliferation and protects pluripotency in culture.1 Inhibits Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK).2

References/Citations:

1) Miyabayashi et al. (2008), Indole derivatives sustain embryonic stem cell self-renewal in long term culture; Biosci. Biotechnol. Biochem., 72 1242
2) Hasegawa et al. (2012), Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion ; Stem Cells Translat. Med., 1 18

ID-8 | DYRK Inhibitor is also available in the Cellular Metabolism Library.
CAS:
147591-46-6
Catalog Number:
10-4506
Activity:
DYRK Inhibitor
Chemical Name:
1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol
Molecular Weight:
298.29
Molecular Formula:
C16H14N2O4
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
Solid
Purity:
99%
NMR (Confirms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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