JZL-184 | MAG lipase inhibitor
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 10 mg | $62.00 | ||
| 50 mg | $248.00 |
JZL-184 (1101854-58-3) inhibits MAG lipase (IC50=8 nM) selectively over FAAH. Irreversible. Cell permeable.
References/Citations:
1) Long et al. (2009), Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects; Nat. Chem. Biol.,5 37
2) Pan et al. (2009), Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxyl)methyl)piperidine-1-carboxylate (JZL 184) enhances retrograde endocannabinoid signaling; J. Pharmacol. Exp. Ther., 331 591
3) Kinsey et al. (2009), Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain; J. Pharmacol. Exp. Ther., 330 902
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
JZL-184 (1101854-58-3) inhibits MAG lipase (IC50=8 nM) selectively over FAAH. Irreversible. Cell permeable.
References/Citations:
1) Long et al. (2009), Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects; Nat. Chem. Biol.,5 37
2) Pan et al. (2009), Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxyl)methyl)piperidine-1-carboxylate (JZL 184) enhances retrograde endocannabinoid signaling; J. Pharmacol. Exp. Ther., 331 591
3) Kinsey et al. (2009), Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain; J. Pharmacol. Exp. Ther., 330 902
Related products
-
Metyrapone | Cytochrome P450 inhibitor
From $30.00CAS:54-36-4Catalog Number:10-1159Activity:Cytochrome P450 inhibitorChemical Name:2-Methyl-1,2-dipyridin-3-yl-propan-1-oneMolecular Weight:226.27Molecular Formula:C14H14N2OSolubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Simvastatin | HMG-CoA reductase inhibitor
From $50.00CAS:79902-63-9Catalog Number:10-1018Activity:HMG-CoA reductase inhibitorAlternate Names:MevinolinChemical Name:2,2-Dimethyl-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester butanoic acidMolecular Weight:418.58Molecular Formula:C25H38O5Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 35 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Zafirlukast | HSP70 inhibitor and leukotriene antagonist
From $28.00CAS:107753-78-6Catalog Number:10-1100Activity:Hsp70 inhibitorAlternate Names:ICI-204219Molecular Weight:575.69Molecular Formula:C31H33N3O6SSolubility:Soluble in DMSO (up to 10 mg/ml).Physical Properties:White or pink solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years as supplied. Protect from exposure to moisture. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
Website Created by Advanta Advertising LLC.