BiochemicalTargets

Lipases

Lipases, which occur in various tissue types and cellular organelles, are serine hydrolases—a serine in their catalytic site plays a critical role in hydrolysis of their targets. They act on diacylglycerols, phospholipids, cholesteryl esters, and triacylglycerols, among others. They function in lipid metabolism, inflammation, and cell signaling.

DAG

LY-2183240 | Anandamide uptake inhibitor

CAS:
874902-19-9
Catalog Number:
10-2636
Activity:
Andamide uptake inhibitor
Chemical Name:
5-([1,1′-Biphenyl]-4-ylmethyl)-N,N,-dimethyl-1H-tetrazole-1-carboxamide
Molecular Weight:
307.35
Molecular Formula:
C17H17N5O
Solubility:
Soluble in DMSO (greater than 25 mg/ml) or in Ethanol (up to 15 mg/ml).
Physical Properties:
White solid
Purity:
98%
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year as supplied. Solutions in DMSO of ethanol may be stored at -20°C for up to 1 month
Shipping Code:
RT

Orlistat | DAG Lipase-α inhibitor

CAS:
96829-58-2
Catalog Number:
10-2448
Activity:
DAG Lipase-α inhibitor
Alternate Names:
Ro18-0647, (-)-Tetrahydrolipstatin
Chemical Name:
N-Formyl-L-leucine (1S)-10[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester
Molecular Weight:
495.75
Molecular Formula:
C29H53NO5
Solubility:
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
Shipping Code:
RT

RHC-80267 | DAG Lipase inhibitor

CAS:
83654-05-1
Catalog Number:
10-1051
Activity:
DAG Lipase inhibitor
Alternate Names:
U-57908
Chemical Name:
1,6-bis(Cyclohexyloximinocarbonyl-amino)hexane
Molecular Weight:
394.53
Molecular Formula:
C20H34N4O4
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
Off-white solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
Shipping Code:
RT
VIEW ALL DAG​ PRODUCTS

MAG

ABX-1431 | MAGL inhibitor

CAS:
1446817-84-0
Catalog Number:
10-4596
Activity:
Potent and selective inhibitor of MAGL
Chemical Name:

1,1,1,3,3,3-Hexafluoropropan-2-yl-4-[[2-(pyrrolidin-1-yl)-4-(trifluoromethyl)phenyl]methyl]piperazine-1-carboxylate

Molecular Weight:
507.40
Molecular Formula:
C20H22F9N3O2
Solubility:
Soluble in DMSO (>25 mg/ml)
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Nonylbenzeneboronic acid | FAAH

CAS:
256383-45-6
Catalog Number:
10-3277
Activity:
FAAH Inhibitor
Chemical Name:
4-n-Nonylbenzeneboronic acid
Alternate Names:
NBBA
Molecular Weight:
248.17
Molecular Formula:
C15H25BO2
Solubility:
Soluble in DMSO (up to 30 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

LY-2183240 | Anandamide uptake inhibitor

CAS:
874902-19-9
Catalog Number:
10-2636
Activity:
Andamide uptake inhibitor
Chemical Name:
5-([1,1′-Biphenyl]-4-ylmethyl)-N,N,-dimethyl-1H-tetrazole-1-carboxamide
Molecular Weight:
307.35
Molecular Formula:
C17H17N5O
Solubility:
Soluble in DMSO (greater than 25 mg/ml) or in Ethanol (up to 15 mg/ml).
Physical Properties:
White solid
Purity:
98%
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year as supplied. Solutions in DMSO of ethanol may be stored at -20°C for up to 1 month
Shipping Code:
RT
VIEW ALL MAG PRODUCTS

Phospholipases

Surfactin | Lipopeptide biosurfactant

CAS:
24730-31-2
Catalog Number:
10-5131
Activity:
Lipopeptide biosurfactant
Source:
Cyclic peptide produced by Bacillus substilis
Molecular Weight:
1036.36 (based on C15 subunit)
Molecular Formula:
C53H93N7O13 (based on C15 subunit)
Solubility:
Soluble in DMSO (15 mg/ml)
Physical Properties:
White to off-white solid
Purity:
>98% TLC; HPLC shows mixture of isomers with C14 and C15 side chains predominating.1
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT

ONO-RS-082 | Phospholipase A2 inhibitor

CAS:
99754-06-0
Catalog Number:
10-1107
Activity:
Phospholipase A2 Inhibitor
Chemical Name:
2-(4-Pentylcinnamoyl)amino-4-chlorobenzoic acid
Alternate Names:
PACA
Molecular Weight:
371.86
Molecular Formula:
C21H22ClNO3
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in ethanol (up to 10 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Quinacrine HCl | Antiprotozoan / Anticancer

CAS:
69-05-6
Catalog Number:
10-4251
Activity:
Antiprotozoan / Anticancer
Chemical Name:
6-Chloro-9-(4-diethylamino-1-methylbutyl)amino-2-methoxyacridine dihydrochloride
Molecular Weight:
472.88
Molecular Formula:
C23H30ClN3O • 2HCl
Solubility:
Soluble in Water (up to at least 25 mg/ml) or in DMSO (up to at least 10 mg/ml)
Physical Properties:
Yellow solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Solutions in water should be made fresh daily.
Shipping Code:
RT
VIEW ALL Phospholipases PRODUCTS

Other

NG-497 | Human ATGL inhibitor

CAS:
2598242-66-9
Catalog Number:
10-4626
Activity:
Human ATGL inhibitor
Chemical Names:
Isopropyl 6-(4-ethoxyphenyl)-4-methoxypicolinate
Molecular Weight:
315.37
Molecular Formula:
C18H21NO4
Solubility:
Soluble in DMSO (25 mg/ml with warming); Ethanol (20 mg/ml)
Physical Properties:
White to off-white solid
Purity:
>98% HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

DO264 | ABHD12 inhibitor

CAS:
2301866-59-9
Catalog Number:
10-3712
Activity:
ABHD12 inhibitor
Chemical Name:
1-(1-(3-Chloro-4-(2-chloro-4-(trifluoromethyl)phenoxy)pyridin-2-yl)piperidin-4-yl)-3-(pyridin-3-yl)thiourea
Molecular Weight:
542.40
Molecular Formula:
C23H20Cl2F3N5OS
Solubility:
Soluble in DMSO (up to 30 mg/ml).
Physical Properties:
Pale yellow solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT

Atglistatin | ATGL inhibitor

CAS:
1469924-27-3
Catalog Number:
10-4598
Activity:
ATGL inhibitor
Chemical Name:
N’-[4’-(Dimethylamino)[1,1’-biphenyl]-3-yl]-N,N,-dimethylurea
Molecular Weight:
283.37
Molecular Formula:
C17H21N3O
Solubility:
Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml with warming)
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
VIEW ALL Other PRODUCTS

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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