Mitomycin C | DNA crosslinking and damaging agent

CAS:
50-07-7
Catalog Number:
10-1170
Activity:
DNA crosslinking and damaging agent
Chemical Name:
Natural fermentation product from Streptomyces sp.
Molecular Weight:
334.33
Molecular Formula:
C15H18N4O5
Solubility:
Soluble in DMSO (up to 15 mg/ml) or in Water (up to 1 mg/ml).
Physical Properties:
Blue-violet solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Storing aqueous solutions is not recommended.
Shipping Code:
RT

Available Options

size :PriceQuantity 
5 mg$55.00
25 mg$190.00

Mitomycin C (50-07-7) is a DNA damaging and crosslinking agent. Induces apoptosis in various cell lines. Cell permeable. This product is not approved for human therapeutic use.

References/Citations:

1) Tee and Proud (2000), DNA-damaging agents cause inactivation of translational regulators linked to mTOR signaling; Oncogene, 30 21
2) Park et al. (2000), Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95- independent manner in human gastric adenocarcinoma cells; Cancer Lett., 158 125
3) Merck Index 14:6215

CAS:
50-07-7
Catalog Number:
10-1170
Activity:
DNA crosslinking and damaging agent
Chemical Name:
Natural fermentation product from Streptomyces sp.
Molecular Weight:
334.33
Molecular Formula:
C15H18N4O5
Solubility:
Soluble in DMSO (up to 15 mg/ml) or in Water (up to 1 mg/ml).
Physical Properties:
Blue-violet solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Storing aqueous solutions is not recommended.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee