MLS-532223 | GTPase inhibitor

CAS:
16616-39-0
Catalog Number:
10-1305
Activity:
GTPase inhibitor
Chemical Name:
1-(3-Nitrophenyl)-3-phenyl-2-propyn-1-one
Molecular Weight:
251.24
Molecular Formula:
C15H9NO3
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
5 mg$62.00
25 mg$248.00

MLS-532223 (16616-39-0) is a high-affinity selective inhibitor of Rho family GTPases (EC50=10 μM). It inhibits EGF-stimulated Rac1 activation (3-10 μM). Cell permeable.

References/Citations:

1) Surviladze et al. (2010), Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay; J. Biomol. Screening, 15 10

CAS:
16616-39-0
Catalog Number:
10-1305
Activity:
GTPase inhibitor
Chemical Name:
1-(3-Nitrophenyl)-3-phenyl-2-propyn-1-one
Molecular Weight:
251.24
Molecular Formula:
C15H9NO3
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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