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MLS-573151 | Cdc42 inhibitor

CAS:
10179-57-4
Catalog Number:
10-1193
Activity:
Cdc42 inhibitor
Chemical Name:
4-[3,5-Diphenyl-4,5-dihydropyrazol-1-yl]benzenesulfonamide
Molecular Weight:
377.47
Molecular Formula:
C21H19N3O2S
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

MLS-573151 (10179-57-4) is a potent and specific inhibitor of Cdc42 a small GTPase of the Rho-subfamily (IC50=2 μM).1 A useful agent fpr probing the involvement of Cdc42 in cellular signaling and physiology.2

References/Citations:

1) Surviladze et al. (2010), Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay; J. Biomol. Screening, 15 10
2) Wang et al. (2017), Cannabinoid Receptor 1 Mediates Homing of Bone Marrow-Derived Mesenchymal Stem Cells Triggered by Chronic Liver Injury; J. Cell Physiol., 232 110

MLS-573151 | Cdc42 inhibitor is also available in the Cellular Metabolism Library.
CAS:
10179-57-4
Catalog Number:
10-1193
Activity:
Cdc42 inhibitor
Chemical Name:
4-[3,5-Diphenyl-4,5-dihydropyrazol-1-yl]benzenesulfonamide
Molecular Weight:
377.47
Molecular Formula:
C21H19N3O2S
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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