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Multiple sclerosis

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  • Benztropine mesylate | Induces remyelination of neurons
    $38.00
    Benztropine mesylate (132-17-2) is a centrally acting M1 muscarinic acetylcholine receptor antagonist (Ki=0.59 nM, rat).1 Also inhibits the dopamine transporter (Ki=160 nM).2 Benztropine mesylate enhances remyelination and...

  • FTY720 HCl | Sphingosine-1-phosphate receptor agonist
    $40.00
    FTY720 HCl (162359-56-0) is an analog of sphingosine (Cat.# 10-2287) which, when taken up into cells, is phosphorylated and acts as an agonist at sphingosine-1-phosphate receptors (S1P1/3).1 Potently inhibits regulatory...

  • MDL29,951 | GPR17 activator
    $85.00
    MDL29,951 (130798-51-5) is a new, highly specific, small molecule activator of GPR171 that has been shown to be active in intact cells1. The ability to specifically activate GPR17 allows for the study of the exact role GPR17...

  • Minocycline HCl | Neuroprotective; antiapoptotic
    $38.00
    Minocycline HCl (13614-98-7) displays antiapoptotic, anti-inflammatory1 activity. Prevents neuropathic pain in a rat sciatic nerve injury model1. Reduces MMP-9 activity2. Attenuates disease severity in mouse models of...

  • SR-1001 | 1335106-03-0 | Structure | Supplier
    $120.00
    SR-1001 (1335106-03-0) is a high affinity synthetic ligand for both RORα and RORγt acting as an inverse agonist. It binds specifically to the ligand-binding domain, inducing a conformational change which leads to...

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