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  • C-646 | 328968-36-1 | Structure | Supplier
    $80.00
    C-646 (328968-36-1) is a potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM ). Induces apoptosis in prostate cancer cells. C-646 enhances fear extinction memory and synaptic plasticity in...

  • Filipin III | 480-49-9 | Structure | Supplier
    $120.00
    Filipin III (480-49-9) is a polyene macrolide antibiotic. It may be used in a double staining procedure for the detection of lipoproteins.1 Binds specifically to cholesterol forming a fluorescent complex which may be used...

  • Leonurine | Neuroinflammation inhibitor
    $48.00
    Inhibits microglial overactivation and attenuates Aβ(1-40)-induced cognitive impairments in rats via JNK and NF-κB pathways.1 Inhibits the formation of advanced glycation end products.2 Ameliorates cognitive...

  • LM22A-4 | 37988-18-4 | Structure | supplier
    $120.00
    LM22A-4 (37988-18-4) is a small molecule BDNF mimetic displaying neurotrophhic activity. Partial agonist at TRKB and activates TRKB signaling. In in vitro models of neurodegenerative disease, it prevented neuronal...

  • MDL29,951 | GPR17 activator
    $85.00
    MDL29,951 (130798-51-5) is a new, highly specific, small molecule activator of GPR171 that has been shown to be active in intact cells1. The ability to specifically activate GPR17 allows for the study of the exact role GPR17...

  • SU-4312 | 5813-07-7 | Structure | Supplier
    $70.00
    SU-4312 (5812-07-7) is a potent selective inhibitor of VEGFR kinase (also known as Flk-1 and KDR). Inhibition of the activated kinase (IC50 = 0.4 μM) is 100-fold less than inhibition of the unactivated kinase (IC50 = 0.04...

  • Tolcapone | COMT inhibitor / TTR aggregation inhibitor
    $50.00
    Tolcapone (134308-13-7) is a catechol O-methyltransferase inhibitor (COMT), inhibiting both brain and peripheral enzymes.1 Potent inhibitor of alpha-synuclein and beta-amyloid oligomerization and fibrillogenesis protecting...

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