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Neuropsych

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  • 6,7-ADTN HBr | Dopamine D1 agonist
    $60.00
    6,7-ADTN HBr (13575-86-5) is a broad spectrum dopamine receptor agonist.1,2  Demonstrates a marked selectivity for the human dopamine D3 receptor.3 6,7-ADTN and psychostimulants such as cocaine and amphetamine reduce...

  • ABT-418 HCl | Nicotinic acetylcholine receptor agonist; cognition enhancer
    $90.00
    Agonist at neuronal nicotinic acetylcholine receptors displaying the highest potency at α4β2 and α2β2 subtypes (EC50= approximately 6 and 11 μM, respectively).1 Displays anxiolytic activity in a rat...

  • ANA-12 | TrkB antagonist
    $87.00
    ANA-12 (219755-25-3) is a TrkB receptor antagonist. Binds to two distinct receptor sites preventing activation by BDNF non-competitively, IC50 = 45.6 nM and 41.1 μM for the high and low affinity sites respectively...

  • Aripiprazole | Dopamine receptor partial agonist
    $40.00
    Aripiprazole (129722-2-9) is a clinically useful neuroleptic and antipsychotic agent.1 Dopamine D2 receptor antagonist and autoreceptor agonist.2 Improves symptoms of psychosis associated with Alzheimer's disease...

  • Clozapine | 5786-21-0 | Structure | Supplier
    $30.00
    Clozapine (5786-21-0) is a dopamine D4 and D2 receptor antagonist. High affinity for the cloned rat dopamine D4 receptor (Ki < 20 nM).1 Atypical neuroleptic agent.2 Antagonist at 5HT2A, 5HT2C, 5HT3, 5HT6 and 5HT7...

  • EPPTB | 1110781-88-8 | Structure | Supplier
    $75.00
    EPPTB (1110781-88-8) is a novel selective trace amine associated receptor 1 (TAAR1) antagonist (IC50=28 nM at mouse TAAR1). A useful tool for probing the physiologic role of TAAR1. References/Citations1) Bradaia et al...

  • Erucamide | Antidepressant/Anti-anxiety
    $25.00
    Erucamide (112-84-5) is an endogenous fatty acid amide.  It was able to ameliorate depression and anxiety-like behaviors in several mouse models.  Significantly lowered levels of circulating adrenocorticotrophic...

  • GBR-12909 2HCl | Dopamine reuptake inhibitor
    $60.00
    GBR-12909 2HCl (67469-78-7) is a potent and selective inhibitor of dopamine reuptake (Ki = 1 nM) with greater than 100 fold selectivity over serotonin and noradrenaline.1 GBR-12909 2HCl also acts as a potent sigma...

  • ML-297 | 1443246-62-5 | Structure | Supplier
    $70.00
    ML-297 (1443246-62-5) is a selective GIRK 1/2 (Kir3.1/3.2) channel activator, IC50 = 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively. Has no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels.1,2...

  • Norquetiapine 2HCl | Quetiapine metabolite
    $60.00
    Norquetiapine 2HCl (111974-74-4) is a pharmacologically active metabolite of quetiapine (Seroquel).1  Exhibits distinct pharmacological activity from quetiapine and plays an important role in its antidepressant activity...

  • Perphenazine | Antipsychotic agent
    $25.00
    Perphenazine (58-39-9) is a clinically useful typical antipsychotic drug.  The therapeutic mode of action is not well understood but it binds to a wide variety of receptors including serotonin, histamine, dopamine, and...

  • Theanine | GABA agonist
    $25.00
    L-Theanine (3081-61-6) is a naturally occurring amino acid found in tea leaves. It is able to cross the blood brain barrier and has been shown to have psychoactive effects1 including cognition improvement, reduction of...

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