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Nitric Oxide and other gaseous mediators

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  • 1400W | iNOS inhibitor
    $40.00
    1400W (214358-33-5) is a potent, tight-binding, slow inhibitor of inducible nitric oxide synthase (iNOS). Highly selective for iNOS3 (Ki = 7 nM) over nNOS or eNOS (Ki's of 2 μM and 50 μM respectively).1 1400W is cell...

  • DEA NONOate | NO Donor
    $25.00
    DEA NONOate (372965-00-9)  is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner.    The half-life of DEA NONOate in 0.1 M phosphate buffer at pH 7.4 is 2 min at 37 °C,...

  • DETA NONOate | NO Donor
    $35.00
    DETA NONOate (146724-94-9) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner. The half-life of DETA NONOate in 0.1 M phosphate buffer at pH 7.4 is 20 hours at 37°C, or 56 hours at...

  • Ebselen | Glutathione peroxidase mimic
    $28.00
    Ebselen (60940-34-3) is a novel nontoxic selenium-containing multifunctional antioxidant and anti-inflammatory agent.1 Displays protective effects in reperfusion injury and stroke.2 Ebselen is an excellent...

  • MnTBAP | 55266-18-7 | Structure | Supplier
    $30.00
    MnTBAP (55266-18-7) is a superoxide dismutase (SOD) mimetic. Potent peroxynitrite scavenger but does not scavenge nitric oxide. References/Citations1) Szabo et al. (1996), Evaluation of the relative contribution of nitric...

  • PAPA NONOate | NO Donor
    $25.00
    PAPA NONOate (146672-58-4) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner. The half-life of PAPA NONOate in 0.1 M phosphate buffer at pH 7.4 is 15 minutes at 37°C, or 77 minutes...

  • Propargylglycine | 64165-64-6 | Structure | Supplier
    $38.00
    Propargylglycine (64165-64-6) is an irreversible inhibitor of the hydrogen sulfide biosynthesis enzyme, cystathione-γ-lyase. It inhibits H2S production in rat liver preparations (IC50=55 μM) and inhibits the rise in...

  • Spermine NONOate | NO Donor
    $30.00
    Spermine NONOate (136587-13-8) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner.    The half-life of Spermine NONOate in 0.1 M phosphate buffer at pH 7.4 is 39 min at 37...

  • TRIM | Nitric oxide synthase inhibitor
    $35.00
    TRIM (25371-96-4) is a potent inhibitor of neuronal and inducible nitric oxide synthases, (IC50 = 28.2 and 27.0 μM respectively). Inhibits endothelial NOS with lower potency (IC50 = 1057.5 μM1. TRIM displays...

  • Trolox | Antioxidant
    $25.00
    Trolox (53188-07-1) is a water soluble derivative of vitamin E. Displays antioxidant and radical scavenging activities1. Prevents lipid peroxidation induced by CYP2E1 in Hep G2 cells2. Trolox inhibits peroxynitrite-mediated...

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