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  • 1,10-Phenanthroline HCl | Zn metalloprotease inhibitor
    1,10-Phenanthroline (18851-33-7) is a high affinity chelator of divalent metal ions and may be used to inhibit zinc metalloenzymes.1  It is a potent inhibitor of JAMM-type isopeptidases (DUBs) acting via chelation of an...

  • Actinonin | Leucyl aminopeptidase inhibitor
    Actinonin (13434-13-4) is a potent hydroxamic acid inhibitor of aminopeptidases which displays analgesic effects by inhibiting enkephalin-degrading enzymes1. Actinonin also inhibits peptide deformylase2. Induces apoptosis...

  • CL-82198 | 307002-71-7 | Structure | Supplier
    CL-82198 (307002-71-7) is a selective inhibitor of MMP-13 (IC50 = 10 μM). It displayed no activity against MMP-1, MMP-9 or TACE. References/Citations1) Chen, et al. (2000), Structure-based design of a novel, potent, and...

  • Ilomastat | GM-6001 | GM6001 | 142880-36-2 | structure | Supplier
    Ilomastat (142880-36-2) is a potent pan-specific inhibitor of matrix metalloproteinases (MMPs).1 Ki values have been reported for the following human MMPs: MMP-1, 0.4nM; MMP-2, 0.5nM; MMP-3, 27nM; MMP-7, 3.7nM; MMP-8, 0.1nM;...

  • NNGH | 161314-17-6 | Structure | supplier
    NNGH (161314-17-6) is a potent pan-specific inhibitor of matrix metalloproteinases ( MMP3 Ki=0.013 μM). Inhibits MMP-1, -2, -7-10, -12-14 and MMP-20. Attenuates inflammation-induced thermal hyperalgesia. Cell Permeable...

  • NSC-405020 | 7497-07-6 | Structure | Supplier
    NSC-405020 (7497-07-6) is a membrane type-1 matrix metalloproteinase (MMP14 or MT1-MMP) inhibitor that prevents homodimerization and inhibits MMP14’s protumorigenic activity in vivo. (IC50 > 100 μM). Inhibition...

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