Ro 13-6438 | PDE3 inhibitor

CAS:
70018-51-8
Catalog Number:
10-1056
Activity:
PDE3 inhibitor
Chemical Name:
(R)-6-Chloro-1,5-dihydro-3-methylimidazo[2,1-b]quinazolin-2-one
Molecular Weight:
235.67
Molecular Formula:
C11H10ClN3
Solubility:
Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 1 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
Shipping Code:
RT

Available Options

Size:PriceQuantity 
10 mg$75.00
50 mg$300.00

Ro 13-6438 (70018-51-8) is a selective inhibitor of phosphodiesterase III (PDE III, IC50 = 0.6 μM).

References/Citations:

1) Eigenmann et al. (1984) Cardiovascular profile of Ro 13-6438, a novel positive inotropic agent with vasodilating properties; J. Cardiovasc. Pharmacol., 6 511
2) Holck et al. (1984) Studies on the mechanism of positive inotropic activity of Ro 13-6438, a structurally novel cardiotonic agent with vasodilating properties; J. Cardiovasc. Pharmacol. 6 520

CAS:
70018-51-8
Catalog Number:
10-1056
Activity:
PDE3 inhibitor
Chemical Name:
(R)-6-Chloro-1,5-dihydro-3-methylimidazo[2,1-b]quinazolin-2-one
Molecular Weight:
235.67
Molecular Formula:
C11H10ClN3
Solubility:
Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 1 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee