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Product Details

Safracin B | Anticancer agent

Safracin B (87578-99-2) is a novel antibiotic of the saframycin family produced by Pseudomonas fluorescens.1 Safracin B displays antitumor activity against L1210 and P388 leukemias and B16 melanoma. Compared with safracin A, the toxic and effective doses were much lower. Safracin B also prolonged the life of tumor-bearing mice to a greater extent than safracin A.2

References/Citations

1) Ikeda et al. (1983), Safracins, new antitumor antibiotics. I. Producing organism, fermentation and isolation; J. Antibiot. Tokyo, 36 1279
2) Okumoto et al. (1985), Activity of safracins A and B, heterocyclic quinone antibiotics, on experimental tumors in mice; J. Antibiot.Tokyo, 38 767

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Catalog#  10-3208-0001

$98.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
87578-99-2
Catalog Number:
10-3208
Activity:
Anticancer agent
Source:
Produced by Pseudomonas fluorescens
Molecular Weight:
540.61
Molecular Formula:
C28H36N4O7
Solubility:
Soluble in DMSO (up to 20 mg/ml)
Physical Properties:
Yellow-green solid
Purity:
90% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
FeaturedDescription:
Displays antitumor activity against L1210 and P388 leukemias and B16 melanoma
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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