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SMER3 | E3 Ubiquitin ligase inhibitor

CAS:
67200-34-4
Catalog Number:
10-1356
Activity:
E3 Ubiquitin ligase inhibitor
Chemical Name:
9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Molecular Weight:
224.18
Molecular Formula:
C11H4N4O2S
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT

SMER3 ( 67200-34-4; Small Molecule Enhancer of Rapamycin 3) is a specific inhibitor if the ubiquitin E3 ligase SCFMET30 both in vitro and in vivo.

References/Citations:

1) Aghajanyy et al. (2010), Chemical genetics of TOR identifies an SCF family E3 ubiquitin ligase inhibitor; Nat. Biotechnol., 28 738

SMER3 | E3 Ubiquitin ligase inhibitor is also available in the Cellular Metabolism Library.
CAS:
67200-34-4
Catalog Number:
10-1356
Activity:
E3 Ubiquitin ligase inhibitor
Chemical Name:
9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Molecular Weight:
224.18
Molecular Formula:
C11H4N4O2S
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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