Spermine NONOate | NO Donor

CAS:
136587-13-8
Catalog Number:
10-4549
Activity:
NO Donor
Chemical Name:
1-{N-[3-Aminopropyl]-N-[4-(3-aminopropylammonio)butyl]-amino}-diazen-1-ium-1,2-diolate
Molecular Weight:
262.35
Molecular Formula:
C10H26N6O2
Solubility:
Soluble in Water or Ethanol
Physical Properties:
Off-white solid
Purity:
97% by (1H-NMR)
Storage Temperature:
-80°C
Stability:
Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Buffer solutions are not stable and must be prepared immediately before use.
Shipping Code:
Blue Ice

Available Options

Size :PriceQuantity 
10 mg$50.00
50 mg$150.00

Spermine NONOate (136587-13-8) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner.    The half-life of Spermine NONOate in 0.1 M phosphate buffer at pH 7.4 is 39 min at 37 °C, or 230 min at room temperature.1    Dissociation is essentially instantaneous at a pH of 5.0.

References/Citations

1) Keefer et al. (1996), “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms; Methods Enzymol., 268 281

CAS:
136587-13-8
Catalog Number:
10-4549
Activity:
NO Donor
Chemical Name:
1-{N-[3-Aminopropyl]-N-[4-(3-aminopropylammonio)butyl]-amino}-diazen-1-ium-1,2-diolate
Molecular Weight:
262.35
Molecular Formula:
C10H26N6O2
Solubility:
Soluble in Water or Ethanol
Physical Properties:
Off-white solid
Purity:
97% by (1H-NMR)
Storage Temperature:
-80°C
Stability:
Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Buffer solutions are not stable and must be prepared immediately before use.
Shipping Code:
Blue Ice

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee