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Product Details

Taxol | Microtubule stabilizing agent

Taxol (33069-62-4) is a clinically useful cancer chemotherapeutic agent for the treatment of breast, non-small cell lung and ovarian cancer.1 Taxol acts as a promoter of tubulin polymerization and stabilizes microtubules in vitro and in vivo resulting in arrest of cells in the G2 and M phase of the cell cycle.2

References/Citations
1) Rowinsky and Donehower (1995) Drug Therapy: Paclitaxel(Taxol); N. Engl. J. Med., 332 1004
2) Schiff and Horwitz (1980) Taxol stabilizes microtubules in mouse fibroblast cells; Proc. Nat. Acad. Sci.USA, 77 1561

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Catalog#  10-2095

$50.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
33069-62-4
Catalog Number:
10-2095
Activity:
Microtubule stabilizing agent
Alternate Names:
Paclitaxel
Molecular Weight:
853.91
Molecular Formula:
C47H51NO14
Solubility:
Soluble in DMSO (up to 50 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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