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  • BI-6015 | 93987-29-2 | Structure | Supplier
    $48.00
    BI-6015 (93987-29-2) is a hepatocyte nuclear factor 4α (HNF4α) antagonist. HNF4α is a central regulator of gene expression in cell types that play a central role in metabolic homeostasis.1 BI-6015 binds to...

  • Fatostatin | 125256-00-0 | Structure | Supplier
    $50.00
    Fatostatin (125256-00-0) blocks adipogenesis by inhibiting the activation of SREBP. Inhibits the ER-Golgi translocation of SREBPs via binding to their escort protein (SCAP). Fatostatin prevents increases in body weight,...

  • Mithramycin A | Transcription inhibitor
    $40.00
    Mithramycin A (18378-89-7) inhibits DNA methyl transferase.1 A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibiting their expression.2...

  • Stauprimide | 154589-96-5 | Structure | Supplier
    $85.00
    Stauprimide (154589-96-5) dramatically primes embryonic stem cells for differentiation. Its molecular target is NME2, a c-Myc-activating transcription factor. Stauprimide inhibits nuclear localization of NME2 thereby...

  • Thiostrepton | Antibiotic and FOXM1 inhibitor
    $85.00
    Thiostrepton (1393-48-2) is a novel cyclopeptide antibiotic. Blocks bacterial protein synthesis by inhibition of mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery as well as...

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