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  • Caerulomycin A | Blocks STAT1 signaling / Immunosuppressant
    Caerulomycin A (21802-37-9) chemically novel and potent immunosuppressive agent. Suppresses T cell activation and IFN7gamma; secretion in vitro and in vivo1. Caerulomycin A induces expansion of regulatory T cells by via...

  • Niclosamide | STAT3 signaling inhibitor
    Niclosamide (50-65-7) reversibly inhibits mTORC1 signaling and stimulates autophagy1. Inhibits activation and nuclear translocation of STAT3 selectively over STAT1 and STAT5. Niclosamide inhibits transcription of STAT3...

  • Stattic | STAT3 inhibitor
    Stattic (19983-44-9) is a STAT3 inhibitor that inhibits binding of tyrosine-phosphorylated peptides to STAT3 SH2 domain and inhibiting STAT3 activation, dimerization and nuclear translocation1. Displays selectivity over...

  • Tofacitinib | JAK inhibitor
    Tofacitinib (477600-75-2) is a potent pan-JAK inhibitor, IC50s=1, 20 and 112 nM for JAK3, JAK2 and JAK1 respectively.1 Displays potent antiinflammatory2 and immunosuppressant3 activity. Promotes a white-to-brown metabolic...

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