Ubiquitin Proteasome Pathways (UPP) are important in a variety of cell processes. UPP products are invaluable for the study of defects in these processes which cause conditions such as cancer, inflammation and DNA damage.
A selective inhibitor of Usp14
a selective inhibitor of the ubiquitin-specific protease
A nonselective, reversible inhibitor of cysteine-reactive deubiquitinating enzymes
A specific and potent autophagy inhibitor
The first small molecule inhibitor of the HECT domain
A specific inhibitor if the ubiquitin E3 ligase
Binds to the E3 ubiquitin ligase complex