Vinblastine sulfate (143-67-9) is a semisynthetic alkaloidal anticancer agent. Induces cell cycle arrest at G₂/M phase by inhibiting mitotic spindle formation.¹ Inhibits normal microtubule assembly and induces aberrant tubulin polymerization.¹ Vinblastine sulfate induces apoptosis in a variety of cell lines.² Inhibits autophagosome maturation.³ Inhibits palmitoylation of tubulin.⁴

References/Citations
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4) Caron and Herwood (2007), Vinblastine, a chemotherapeutic drug, inhibits palmitoylation of tubulin in human leukemic lymphocytes; Chemotherapy, 53 51