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Product Details

WHI-P131 | JAK3 inhibitor

WHI-P131 (202475-60-3) is a JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion1. Increases survival in a mouse ALS model2.

References/Citations
1) Narla et al. (1998), Inhibition of human glioblastoma cell adgesion and invasion by 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline (WHI-P131) and 4-(3'-bromo-4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline (WHI-P154); Mol. Clin. Cancer Res., 42463
2) Trieu et al. (2000), A specific inhibitor of janus kinase-3 increases survival in a transgenic mouse model of amyotrophic lateral sclerosis; Biochem. Biophys. Res. Commun., 267 22

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WHI-P131 | 202475-60-3 | Structure | Supplier

Catalog#  10-1190

$50.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
202475-60-3
Catalog Number:
10-1190
Activity:
JAK3 inhibitor
Alternate Names:
JANEX-1
Chemical Name:
4-[(4'-hydroxyphenyl)amino]-6,7-dimehtoxyquinazoline
Molecular Weight:
333.78
Molecular Formula:
C16H15N3O3 HCl
Solubility:
Soluble in DMSO (up to 50 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years as supplied. Protect from moisture. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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