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Product Details

4,9-Anhydrotetrodotoxin | Selective sodium channel blocker

4,9-Anhydrotetrodotoxin (13072-89-4) is a highly selective blocker of the Na(v1.6) sodium channel. (IC50's: Na(v1.2) = 260 nM, Na(v1.3) = 341 nM, Na(v1.4) = 988 nM, Na(v1.5) = 11.6 μM, Na(v1.6) = 7.8 nM, Na(v1.7) = 1.27 μM, Na(v1.8) = >30 μM.).1

References/Citations
1) Rosker et al. (2007), The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na(v1.6) voltage-dependent sodium channel; Am.J.Physiol.Cell Physiol., 293 C783.

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Focus Biomolecules supplier, chemical structure 4,9-Anhydrotetrodotoxin | Selective sodium channel blocker | CAS 13072-89-4

Catalog#  10-3700

$125.00
Quantity
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CAS:
13072-89-4
Catalog Number:
10-3700
Activity:
Selective sodium channel blocker
Molecular Weight:
301.25
Molecular Formula:
C11H15N3O7
Solubility:
Soluble in Ethanol (up to 10 mg/ml).
Physical Properties:
Colorless film
Purity:
>98% by HPLC
NMR (Conforms)
High Res. Mass (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years as supplied. Protect from exposure to light or moisture. Solutions are not stable. Solutions must be prepared fresh and used within 1 working day.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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