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6-Formylindolo[3,2-b]carbazole | AhR endogenous agonist

6-Formylindolo(3,2-b)carbazole (172922-91-7) is a very potent (Kd = 0.07 nM) endogenous ligand for the aryl hydrocarbon receptor (AhR).1,2

References/Citations
1) Rannung et al. (1987) Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances; J. Biol. Chem., 262 15422
.2) Wincent et al. (2009) The Suggested Physiologic Aryl Hydrocarbon Receptor Activator and Cytochrome P4501 Substrate 6-Formylindolo[3,2-b}carbazole is Present in Humans; J. Biol. Chem., 284 2690

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Focus Biomolecules supplier, chemical structure of 6-Formylindolo[3,2-b]carbazole | AhR endogenous agonist | CAS 172922-91-7

Catalog#  10-1463

$49.00
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CAS:
172922-91-7
Catalog Number:
10-1463
Activity:
AhR endogenous agonist
Alternate Names:
FICZ
Molecular Weight:
284.32
Molecular Formula:
C19H12N2O
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
Yellow solid
Purity:
95% by TLC
NMR (Conforms)
Storage Temperature:
-80°
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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