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  • Focus Biomolecules cell signaling reagent supplier, chemical structure of PD173074 | FGFR inhibitor | CAS 219580-11-7
    PD173074 (219580-11-7)is an inhibitor of FGFR tyrosine kinase, and to a lesser extent VEGFR1 (IC50 values are 5 nM, 22.5 nM and 100 nM for FGFR1, FGFR3 and VEGFR respectively). Inhibition of FGFR by PD173074 promotes stem...

  • Focus Biomolecules cell signaling reagent supplier, structure of Thalidomide | E3 UB ligase inhibitor | CAS 50-35-1
    Thalidomide (50-35-1) binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A, and inhibits the ligase activity. Inhibits TNF synthesis and FGF-induced angiogenesis. Cell permeable. Handle with caution,...

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