Approved Drugs
Showing 1–12 of 175 results
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Antivirals
5-Fluorouridine | Proapoptotic antiproliferative agent
Trifluorothymidine (70-00-8) is an analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity.1,2 After p...$45.00 – $165.00 Select options -
Approved Drugs
6-Thioguanine | Anticancer agent / Downregulates DNMT1
6-Thioguanine (154-42-7) is a methyltransferase inhibitor. After incorporation into DNA, it disrupts cytosine methylation by DNA methyltransferase...$30.00 – $110.00 Select options -
Approved Drugs
9-Hydroxyrisperidone | Risperidone metabolite
9-Hydroxyrisperidone (144598-75-4) is a pharmacologically active metabolite of risperidone, an atypical antipsychotic agent.1 Displays high affinit...$30.00 – $110.00 Select options -
Approved Drugs
Abemaciclib | Potent and selective CDK 4/6 inhibitor
Abemaciclib (1231930-82-7) is a potent and selective CDK4/6 inhibitor (IC50 = 2 nM and 10 nM respectively).1 It caused G1 cell cycle arrest in colo...$50.00 – $115.00 Select options -
New Products
Acalabrutinib Supplier | CAS 1420477-60-6 | Focus Biomolecules
Acalabrutinib (1420477-60-6) is a highly selective, potent (IC50 = 3 nM), and irreversible inhibitor of Bruton’s tyrosine kinase (BTK).1 Improved t...$45.00 – $145.00 Select options -
Approved Drugs
Afatinib | EGFR and HER2 inhibitor
Afatinib (850140-72-6) is a clinically useful kinase inhibitor approved for the treatment of non-small cell lung cancer. It is a potent and highly ...$85.00 – $285.00 Select options -
ALK
Alectinib | Potent and selective ALK inhibitor
Alectinib (1256580-46-7) is a potent (IC50 = 1.9 nM) and highly selective ALK inhibitor.1 It blocked phosphorylation of both native ALK and the L11...$60.00 – $205.00 Select options -
Approved Drugs
Allopregnanolone | GABA-A positive allosteric modulator
Allopregnanolone (516-54-1) is an endogenous neurosteroid which acts as a positive allosteric modulator of GABAA receptors.1,2 Recently FDA approve...$70.00 – $280.00 Select options -
Antioxidants
Ambroxol HCl | Free radical scavenger
Ambroxol HCl (18683-91-5) is a radical scavenger with anti-inflammatory activity. Blocks the generation of reactive oxygen species by bronchoalveol...$50.00 – $100.00 Select options -
Apoptosis
Amifostine | Cellular protectant
Amifostine (20537-88-6) is a broad sprectrun radio- and chemoprotective agent.1 Prevents chemotherapy-induced apoptosis, upregulates HIF-1α and res...$56.00 – $224.00 Select options -
Approved Drugs
Amiodarone HCl | Pan-specific ion channel blocker
Amiodarone HCl (19774-82-4) is a nonselective ion channel blocker. Class III antiarrhythmic.1 Induces cytochrome c release and induces apoptosis.2 ...$45.00 Select options -
Approved Drugs
Anagrelide HCl | PDE3 inhibitor
Anagrelide HCl (58579-51-4) is a potent and selective phosphodiesterase (PDE3) inhibitor, IC50=36 nM).1 Inhibits platelet production by disrupting ...$48.00 – $200.00 Select options
