Minoxidil | KATP channel opener

Minoxidil (38304-91-5) is a direct antihypertensive peripheral vasodilator acting via activation of KATP channels leading to relaxation of smooth muscle.1 Active metabolite is minoxidil sulfate (IC50 = 0.14 μM). Minoxidil is mainly used as a treatment for alopecia because of its observed hair regrowth ability.2

References/Citations
1) Meisheri et al. (1988), Mechanism of action of minoxidil sulfate-induced vsodialtion: a role for increased K+ permeability; J. Pharmacol. Exp. Ther., 245 7
2) Messenger and Rundegren (2004) Minoxidil:mechanisms of action on hair growth; Br. J. Dermatol., 150 186

Weight 0.01 mg
Dimensions 0.01 × 0.01 × 0.01 cm
size :

100 mg, 500 mg

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CAS:
38304-91-5
Catalog Number:
10-1214
Activity:
KATP channel opener
Chemical Name:
6-Piperidine-1-ylpyrimidine-2,4-diamine 3-oxide
Molecular Weight:
209.25
Molecular Formula:
C9H15N5O
Solubility:
Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Minoxidil | KATP channel opener

$56.00$224.00

CAS:
38304-91-5
Catalog Number:
10-1214
Activity:
KATP channel opener
Chemical Name:
6-Piperidine-1-ylpyrimidine-2,4-diamine 3-oxide
Molecular Weight:
209.25
Molecular Formula:
C9H15N5O
Solubility:
Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
  • 100 mg
  • 500 mg
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