Approved Drugs
Showing 133–144 of 211 results
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Approved Drugs
Nicardipine HCl | L-type Ca channel blocker / MDR inhibitor
Nicardipine (54527-84-3) is a clinically useful L-type calcium blocker. Inhibitor of MDR.2 References/Citations: 1) Merck 14 6495 2) Hulubei...$30.00 – $50.00 Select options -
Approved Drugs
Niclosamide | STAT3 signaling inhibitor
Niclosamide (50-65-7) reversibly inhibits mTORC1 signaling and stimulates autophagy.1 Inhibits activation and nuclear translocation of STAT3 select...$28.00 – $84.00 Select options -
Approved Drugs
Nifedipine | L-type Ca channel blocker
Nifedipine (21829-25-4) is a clinically useful L-type calcium blocker. References/Citations: 1) Vater et al., (1972), (Pharmacology of 4-(2'-...$40.00 – $122.00 Select options -
Apoptosis
Nilotinib | BCR-ABL inhibitor
Nilotinib (CAS 641571-10-0) is a novel, selective BCR-ABL inhibitor. More potent than imatinib against wild-type BCR-ABL (IC50 < 30 nM).1 Induc...$30.00 – $90.00 Select options -
Alzheimers
Nilvadipine | Syk inhibitor/Calcium channel blocker
Nilvadipine (75530-68-6) is a novel DHP L-type Ca2+ channel blocker that also inhibits Syk.1 Blocks Aβ production, APPβ secretion and reduces BACE-...$70.00 – $250.00 Select options -
Approved Drugs
Nimodipine | L-type calcium channel blocker
Nimodipine (66085-59-4) is an L-type calcium channel blocker.1 Prevents age-induced learning deficits in a rat model.2 Facilitates recovery of func...$50.00 – $180.00 Select options -
Antivirals
Nitazoxanide | Wnt signaling inhibitor
Nitazoxanide (55981-09-4) has been found to inhibit Wnt signaling independent of adenomatous polyposis coli (APC) – it targets peptidyl arginine de...$40.00 – $150.00 Select options -
New Products
Nitisinone | Tyrosine metabolism inhibitor
Nitisinone (104206-65-7) is an inhibitor of 4-Hydroxyphenylpyruvate dioxygenase (HPPD; IC50 = 40 nM1 and 173 nM2) and is in clinical use for the tr...$25.00 – $95.00 Select options -
Approved Drugs
Nitrendipine | L-type Ca channel blocker
Nitrendipine (39562-70-4) is a clinically useful L-type calcium blocker. References/Citations: 1) Meyer et al., (1981), (Synthesis and compar...$75.00 – $200.00 Select options -
Approved Drugs
Norquetiapine 2HCl | Quetiapine metabolite
Norquetiapine 2HCl (111974-74-4) is a pharmacologically active metabolite of quetiapine (Seroquel).1 Exhibits distinct pharmacological activity fr...$60.00 – $240.00 Select options -
Adipogenesis
Obeticholic Acid | FXR agonist
Obeticholic acid (459789-99-2) is a novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholereti...$50.00 – $200.00 Select options -
Approved Drugs
Olaparib | PARP1 inhibitor
Olaparib (763113-22-0) is a highly potent and selective PARP-inhibitor with IC50 values of 5 nM and 1 nM for PARP-1 and PARP-2, respectively.1 In ...$45.00 – $130.00 Select options
