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BiochemicalTargets

Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • 5-Azacytidine | DNA hypomethylation agent

    CAS:
    320-67-2
    Catalog Number:
    10-1267
    Activity:
    DNA hypomethylation agent
    Alternate Names:
    Ladakamycin; U-18496; NSC-102816; AzaC
    Chemical Name:
    4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
    Molecular Weight:
    244.21
    Molecular Formula:
    C8H12N4O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $20.00
  • 5-Fluorouracil | Inhibitor of thymidylate synthase

    CAS:
    51-21-8
    Catalog Number:
    10-1276
    Activity:
    Inhibitor of thymidylate synthase
    Alternate Names:
    5-FU
    Chemical Name:
    5-Fluoro-1H,3H-pyrimidine-2,4-dione
    Molecular Weight:
    130.08
    Molecular Formula:
    C4H3FN2O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $20.00
  • 5-Fluorouridine | Proapoptotic antiproliferative agent

    CAS:
    316-46-1
    Catalog Number:
    10-1277
    Activity:
    Proapoptotic antiproliferative agent
    Chemical Name:
    1-(β-D-Ribofuranosyl)-5-fluorouracil
    Alternate Names:
    FUrd
    Molecular Weight:
    262.19
    Molecular Formula:
    C9H11FN2O6
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), in Water (up to 50 mg/ml), or in Ethanol (up to 6 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, distilled water or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • 6-Mercaptopurine | Purine antimetabolite and immunomodulator

    CAS:
    6112-76-1
    Catalog Number:
    10-4698
    Activity:
    Purine antimetabolite and immunomodulator
    Chemical Names:
    3,7-Dihydropurine-6-thione monohydrate
    Alternate Name:
    6-MP
    Molecular Weight:
    170.19
    Molecular Formula:
    C5H4N4S·H2O
    Solubility:
    Soluble in DMSO (>50 mg/ml); ethanol (5 mg/ml with warming)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $25.00
  • 6-Thioguanine | Anticancer agent / Downregulates DNMT1

    CAS:
    154-42-7
    Catalog Number:
    10-1282
    Activity:
    Anticancer agent / Downregulates DNMT1
    Chemical Name:
    2-Amino-6-mercaptopurine
    Alternate Names:
    6-TG; NSC 752, NSC 76504
    Molecular Weight:
    167.19
    Molecular Formula:
    C5H5N5S
    Solubility:
    Soluble in DMF (up to 1.5 mg/ml with warming)
    Physical Properties:
    Pale yellow solid
    Purity:
    96% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMF may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
  • 9-Hydroxyrisperidone | Risperidone metabolite

    CAS:
    144598-75-4
    Catalog Number:
    10-2300
    Activity:
    Risperidone metabolite
    Chemical Name:
    3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
    Alternate Name:
    Paliperidone
    Molecular Weight:
    426.48
    Molecular Formula:
    C23H27FN4O3
    Solubility:
    Soluble in DMSO (up to 4 mg/ml).
    Physical Properties:
    White solid
    Purity:
    95% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $30.00
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