Approved Drugs
Showing 25–36 of 192 results
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Approved Drugs
Clodronate 2Na | Induces osteoclast apoptosis
Clodronate 2Na (88416-50-6) is a first generation non-nitrogenous bisphosphonate drug for the prevention and treatment of osteoporosis and skeletal...$30.00 – $70.00 Select options -
Approved Drugs
Clozapine | Dopamine D2/D4 antagonist
Clozapine (5786-21-0) is a dopamine D4 and D2 receptor antagonist. High affinity for the cloned rat dopamine D4 receptor (Ki < 20 nM).1 Atypical...$30.00 – $100.00 Select options -
Apoptosis
Colchicine | Microtubule depolymerizer
Colchicine (64-86-8) is a naturally occurring alkaloid which acts as an antimitotic agent by binding to tubulin and depolymerizing microtubules. Co...$40.00 – $145.00 Select options -
ALK
Crizotinib | c-MET and ALK inhibitor
Crizotinib (877399-52-5) is a potent and selective inhibitor of c-MET and ALK, IC50's=8 and 20 nM respectively.1 Inhibition of cell proliferation w...$80.00 – $300.00 Select options -
Approved Drugs
Cyclothiazide | AMPA receptor positive allosteric modulator
Cyclothiazide (2259-96-3) is a positive allosteric modulator of AMPA receptors acting at a site distinct from that of 2,3-benzodiazepines.1,2 Clini...$50.00 – $200.00 Select options -
Approved Drugs
D(+)-Cycloserine | NMDA, glycine site partial agonist
D-Cycloserine (68-41-7) is a partial agonist at the glycine modulatory site of NMDA glutamatergic receptors.1 Blocks kainate-induced seizures2 and ...$60.00 – $240.00 Select options -
Approved Drugs
Dabrafenib | B-Raf mutant inhibitor
Dabrafenib (1195765-45-7) is a selective inhibitor of mutant B-RafV600E (IC50 = 0.8 nM), with 4- and 6-fold reduced potency against wild type B-Raf...$34.00 – $150.00 Select options -
Approved Drugs
Dantrolene Na | SR calcium release inhibitor
Dantrolene Na (14663-23-1) inhibits release of Ca2+ from sarcoplasmic reticulum via inhibition of ryanodine receptor channels with selectivity for ...$50.00 – $90.00 Select options -
Approved Drugs
Daptomycin | Antibiotic
Daptomycin (103060-53-3) is a cyclic anionic lipopeptide calcium-dependent antibiotic.1 Useful for the treatment of serious Gram-positive infection...$44.00 – $162.00 Select options -
New Products
Darunavir | HIV-1 protease inhibitor
Darunavir (206361-99-1) is a very potent (IC50 = 3 nM against lab HIV-1 strains and clinical isolates) HIV-1 protease inhibitor that is in clinical...$60.00 – $200.00 Select options -
Approved Drugs
Dasatinib | Src and Bcr/Abl inhibitor
Dasatinib (302962-49-8) inhibits Src, Bcl/Abl and Lyn tyrosine kinases (IC50= 0.55, 3.0 and 8.5 nM respectively).1,2 Suppresses invasion and induce...$50.00 – $95.00 Select options -
Apoptosis
Daunorubicin HCl | DNA Damaging Agent / Anticancer Agent
Daunorubicin HCl (23541-50-6) is an antitumor antibiotic used in the treatment of acute myeloid leukemias.1 Induces DNA damage by intercalation.2 I...$60.00 – $190.00 Select options
