Modify Search
Select all
Products
Pages
Posts
Modify Search
Select all
Products
Pages
Posts

Ouabain | Na+/K+ ATPase inhibitor

CAS:
11018-89-6
Catalog Number:
10-1248
Activity:
Na+/K+ ATPase inhibitor
Chemical Name:
3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11_,14,19-pentahydoxycard-20(22)-enolide octahydrate
Molecular Weight:
728.79
Molecular Formula:
C29H44O12·8(H2O)
Solubility:
Soluble in DMSO (up to 50 mg/ml), or in Water (up to 10 mg/ml).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Protect from exposure to moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Ouabain (11018-89-6) is a selective inhibitor of Na+ K+-ATPase isolated from Strophanthus gratus.1 Endogenous ouabain is found in human circulation.2 Displays cardiotonic and diuretic activity. May be used to induce hypertensive rat model.3 Cell permeable and active in vivo.

References/Citations:

1) Silva et al. (2012), New insights into the regulation of Na+,K(+)-ATPase by ouabain; Int. Rev. Cell. Mol. Biol., 294 99
2) Dvela et al. (2012), Endogenous ouabain regulates cell viability; Am. J. Physiol. Cell, Physiol., 302 C442

Ouabain | Na+/K+ ATPase inhibitor is also available in the Cellular Metabolism Library.
CAS:
11018-89-6
Catalog Number:
10-1248
Activity:
Na+/K+ ATPase inhibitor
Chemical Name:
3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11_,14,19-pentahydoxycard-20(22)-enolide octahydrate
Molecular Weight:
728.79
Molecular Formula:
C29H44O12·8(H2O)
Solubility:
Soluble in DMSO (up to 50 mg/ml), or in Water (up to 10 mg/ml).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Protect from exposure to moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Add to Quote

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee