Bioactive Lipids
Cholesterol Docosanoids Eicosanoids Fatty Acid Binding Protein Fatty acids Lipid biosynthesis inhibitors Lipid metabolism inhibitors Lipid receptor agonists & antagonists Octadecanoids Other Bioactive Lipids PAF Phosphatidic acid Prostaglandins Sphingolipids Steroids
Showing 1–12 of 81 results
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Bioactive Lipids
1-Aminobenzotriazole | Cytochrome P450 inhibitor
1-Aminobenztriazole (1614-12-6) is a pan-specific cytochrome P450 inhibitor acting as a suicide substrate.1,2 Blocks omega-oxidation of arachidonic...$50.00 – $185.00 Select options -
Bioactive Lipids
2-Bromopalmitic acid | Palmitoylation inhibitor
2-Bromopalmitic acid (18263-25-7) inhibits protein S-palmitoylation.1 Blocks palmitic acid-induced increase in cAMP levels in human primary melanoc...$40.00 – $100.00 Select options -
New Products
ABX-1431 | MAGL inhibitor
ABX-1431 is potent (IC50 = 14 nM in vitro, 2.2 nM in human PC3 cells) and very selective (>100-fold over hABHD6, >200-fold over hPLA2G7) inhi...$60.00 – $235.00 Select options -
Bioactive Lipids
Acetyl-Coenzyme A 3Li | Acetylation and fatty acid biosynthesis cofactor
Acetyl-CoA (75520-41-1) is an essential cofactor for cellular metabolism, being an ‘activated acetate’ that shuttles its moieties back and forth du...$65.00 – $260.00 Select options -
Bioactive Lipids
AH-6809 | Prostanoid EP antagonist
AH-6809 (33458-93-4) is a selective PGE2 receptor (EP1) antagonist. At concentrations higher than 10 μM PGD2 and TXA2 receptors are also blocked. ...$60.00 – $240.00 Select options -
Bioactive Lipids
AH-7614 | GPR120 antagonist
AH-7614 (6326-06-3) is a selective antagonist at free fatty acid receptor 4 (FFA4), also known as GPR120. pIC50s= 7.1 and 1. References/Citation...$45.00 – $180.00 Select options -
Bioactive Lipids
AK-7 | SIRT2 inhibitor
AK-7 (420831-40-9) is a selective Sirt2 inhibitor (IC50=15.5 μM) which does not inhibit Sirt1 or Sirt3.1 It down regulates cholesterol biosynthesis...$50.00 – $185.00 Select options -
Approved Drugs
Allopregnanolone | GABA-A positive allosteric modulator
Allopregnanolone (516-54-1) is an endogenous neurosteroid which acts as a positive allosteric modulator of GABAA receptors.1,2 Recently FDA approve...$70.00 – $280.00 Select options -
Bioactive Lipids
Anandamide | Endogenous cannabinoid
Anandamide (94421-68-8) is an endogenous cannabinoid receptor agonist.1-3 Ki=89 nM for CB1 and 371 nM for CB2 receptors. References/Citations 1...$35.00 – $120.00 Select options -
Apoptosis
Baicalein | Inhibitor of protein tyrosine kinase in leukemia (CEM cells)
Baicalein (491-67-8) is an inhibitor of protein tyrosine kinase in leukemia (CEM) cells. Induces cell cycle arrest and apoptosis.1 Originally repor...$40.00 – $148.00 Select options -
Bioactive Lipids
BML-111 | LXA agonist, antiinflammatory
BML-111 (78606-80-1) novel truncated analog of lipoxin A4 which retains anti-inflammatory activity.1 Inhibits LTB4-induced leukocyte chemotaxis, IC...$50.00 – $200.00 Select options -
Bioactive Lipids
BMS-303141 | ATP citrate lyase (ACL) inhibitor
BMS-303141 (943963-47-8) is a potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 μM. Inhibits lipid biosynthesis, IC50=8 μM in HepG2...$70.00 – $280.00 Select options
