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  • Focus Biomolecules supplier, chemical structure of Anandamide | Endogenous cannabinoid | CAS 94421-68-8
    Anandamide (94421-68-8) is an endogenous cannabinoid receptor agonist.1-3 Ki=89 nM for CB1 and 371 nM for CB2 receptors. References/Citations1) Devane et al. (1992), Isolation and structure of a brain constituent that binds...

  • Focus Biomolecules cell signaling reagent supplier, structure of EPA free acid | omega-3 fatty acid | CAS 10417-94-4
    EPA free acid (10417-94-4) dietary enrichment may have anti-inflammatory effects by inhibiting the 5-lipoxygenase pathway and LTB4-mediated neutrophil functions.1 Displays various cardiovascular protective properties.2...

  • N-Arachidonoyldopamine | Endogenous TRPV1 activator
    N-Arachidonoyldopamine (199875-69-9) is an endogenous conjugate of arachidonic acid and dopamine.1 May be the “endogenous capsaicin like substance” in the CNS acting at TRPV1 channels, EC50~ 50 nM1. Also acts as...

  • N-Eicosanoyl serotonin | Neuroprotective
    N-eicosanoyl serotonin is a natural product found in coffee which synergizes with caffeine in protecting the brain in models of α-synucleinopathy1. It inhibits the PP2A methylesterase maintaining PP2A in a highly...