Lipid biosynthesis inhibitors
Showing 1–12 of 17 results
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Bioactive Lipids
AK-7 | SIRT2 inhibitor
AK-7 (420831-40-9) is a selective Sirt2 inhibitor (IC50=15.5 μM) which does not inhibit Sirt1 or Sirt3.1 It down regulates cholesterol biosynthesis...$55.00 – $220.00 Select options -
Bioactive Lipids
BMS-303141 | ATP citrate lyase (ACL) inhibitor
BMS-303141 (943963-47-8) is a potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 μM. Inhibits lipid biosynthesis, IC50=8 μM in HepG2...$70.00 – $280.00 Select options -
Apoptosis
Cerulenin | Fatty Acid Synthase inhibitor
Cerulenin (17397-89-6) is a fatty acid synthase (FAS) inhibitor. Binds to β-keto-acyl-ACP synthase (KAS; IC50=1.5 μM), thus inhibiting protein acyl...$120.00 – $480.00 Select options -
Bioactive Lipids
Fasnall HCl | Fatty acid synthase inhibitor
Fasnall (CAS 929978-58-5) is a potent and selective fatty acid synthase (FASN) inhibitor acting via interfering with cofactor binding.1 IC50s = 147...$66.00 – $264.00 Select options -
Adipogenesis
Fatostatin | SREBP activation inhibitor
Fatostatin (125256-00-0) blocks adipogenesis by inhibiting the activation of SREBP. Inhibits the ER-Golgi translocation of SREBPs via binding to th...$50.00 – $200.00 Select options -
Bioactive Lipids
Fumonisin B1 | Blocks sphingolipid biosynthesis
Fumonisin B1 (116355-83-0) inhibits ceramide synthesis (sphinganine N-acyltransferase), IC50 = 100 nM. Inhibits de novo sphingolipid biosynthesis (...$120.00 – $500.00 Select options -
New Products
Gliotoxin | Immunomodulator
Gliotoxin (67-99-2) is a fungal metabolite with immunosuppressive properties; blocks phagocytosis, cytokine production and proliferation of T and B...$85.00 – $340.00 Select options -
Antioxidants
Hinokitiol | Iron Chelator antioxidant
Hinokitiol (499-44-5) is a potent metal chelator that induces differentiation and apoptosis in teratocarcinoma F9 cells.1 It acts as a reversible i...$52.00 – $175.00 Select options -
Bioactive Lipids
Hymeglusin | Mevalonate biosynthesis inhibitor
Hymeglusin (29066-42-0) is an inhibitor of eukaryotic mevalonate biosynthesis via inhibition of HMG-CoA synthase, IC50=0.12 μM.1 Acts via covalent ...$215.00 – $500.00 Select options -
Approved Drugs
Lovastatin | HMG-CoA reductase inhibitor
Lovastatin (75330-75-5) Blocks cholesterol and isoprenoid biosynthesis via inhibition of HMG-CoA reductase (Ki=1nM for acid form).1,2 Induces apopt...$50.00 – $165.00 Select options -
Approved Drugs
Metyrapone | Cytochrome P450 inhibitor
Metyrapone (54-36-4) inhibits cytochrome P450-mediated prostaglandin omega hydroxylation. Inhibits steroid 11β-hydroxylase thereby inhibiting corti...$30.00 – $120.00 Select options -
Bioactive Lipids
MK-886 | FLAP inhibitor
MK-886 (118414-82-7) is an inhibitor of leukotriene biosynthesis(IC50 = 2.5 nM in human PMN)1 via 5-lipoxygenase-activating protein (FLAP) inhibiti...$70.00 – $280.00 Select options
