Lipid receptor agonists & antagonists
Showing all 12 results
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Bioactive Lipids
AH-6809 | Prostanoid EP antagonist
AH-6809 (33458-93-4) is a selective PGE2 receptor (EP1) antagonist. At concentrations higher than 10 μM PGD2 and TXA2 receptors are also blocked. ...$60.00 – $240.00 Select options -
Bioactive Lipids
AH-7614 | GPR120 antagonist
AH-7614 (6326-06-3) is a selective antagonist at free fatty acid receptor 4 (FFA4), also known as GPR120. pIC50s= 7.1 and 1. References/Citation...$45.00 – $180.00 Select options -
Bioactive Lipids
CYM-5541 | Allosteric sphingosine-1-phosphate receptor 3 agonist
CYM-5541 (945128-26-7) is a potent and selective allosteric agonist of the sphingosine-1-phosphate receptor 3 (S1P3; EC50’s = 72.3-132 nM).1,2 R...$45.00 – $155.00 Select options -
Bioactive Lipids
Grapiprant | EP4 Receptor antagonist
Grapiprant (415903-37-6) is a potent (Ki = 13 nM for human and 20 nM for rat) and selective prostaglandin EP4 receptor antagonist.1 It produces ant...$85.00 – $295.00 Select options -
Bioactive Lipids
GRI-977143 | LPA2 antagonist
GRI-977143 (325850-81-5) is a selective agonist of the lysophosphatidic acid-2 (LPA2) receptor. Displays antiapoptotic activity.1 Rescues apoptotic...$80.00 – $320.00 Select options -
Bioactive Lipids
H2L5186303 | LPA2 antagonist
H2L5186303 (139262-76-3) is a potent and selective lysophosphatidic acid 2 (LPA2) receptor antagonist. IC50 = 8.9 nM, 1230 nM and 27.35 μM for LPA...$60.00 – $200.00 Select options -
Bioactive Lipids
LY-171883 | Cys LT1 antagonist
LY-171883 (88107-10-2) is a selective and orally active leukotriene D4 (LTD4) antagonist (Ki = 0.63 μM).1 It is also an activator of peroxisome pro...$60.00 – $240.00 Select options -
Bioactive Lipids
MK-571 | Cys LT1 antagonist
MK-571 (115104-28-4) is a potent (EC50 = 1.3nM) and selective Leukotriene D4 antagonist (LTD4)1 displaying inverse agonist activity2. Blocks bindin...$60.00 – $240.00 Select options -
Bioactive Lipids
N-Arachidonoyldopamine | Endogenous TRPV1 activator
N-Arachidonoyldopamine (199875-69-9) is an endogenous conjugate of arachidonic acid and dopamine.1 May be the “endogenous capsaicin like substance”...$46.00 – $182.00 Select options -
New Products
Picotamide | Antiplatelet agent
Picotamide (32828-81-2) is an antiplatelet agent that inhibits both thromboxane A2 and thromboxane A2 synthase.1-3 References/Citations: Mo...$75.00 – $295.00 Select options -
Angiogenesis
WEB-2086 | PAF receptor antagonist
WEB-2086 (105219-56-5) is a potent and selective antagonist of the platelet activating factor (PAF) receptor (Ki = 16.3 nM).1 Displays an activity ...$40.00 – $98.00 Select options -
Approved Drugs
Zafirlukast | HSP70 inhibitor and leukotriene antagonist
Zafirlukast (107753-78-6) is a competitive and selective leukotriene receptor antagonist.1 Also inhibits calcium ionophore induced production of le...$28.00 – $55.00 Select options
