Bioinorganic Chemistry

1,10-Phenanthroline HCl | Zn metalloprotease inhibitor

$20.00

1,10-Phenanthroline (18851-33-7) is a high affinity chelator of divalent metal ions and may be used to inhibit zinc metalloenzymes.1 It is a potent inhibitor of JAMM-type isopeptidases (DUBs) acting via chelation of an...

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Bleomycin sulfate | Induces double strand DNA breaks

$90.00

Bleomycin sulfate (9041-93-4) co ordinates with metals producing reactive oxygen species which causes oxidative damage to DNA1 and RNA2. Induces double-strand DNA damage3. Commonly used to induce lung fibrosis in animal...

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Divin | Divisome assembly inhibitor

$75.00

Divin is an iron, cobalt, and copper chelator that arrests the late stages of cytokinesis in bacteria by blocking the physical process of constriction in dividing cells without affecting FtsZ. Iron starvation leads to...

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TPEN | Intracellular Zn2+ chelator

$86.00

TPEN (16858-02-9) is a cell permeable metal chelator. Frequently used to study effects of zinc depletion on cellular processes.1,2 References/Citations1) Chimienti et al. (2001) Role of cellular zinc in programmed cell...

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U-74389G | Free radical scavenger

$95.00

U-74389G (153190-29-5) is an antioxidant and Inhibits iron-mediated lipid peroxidation.1 It has also been shown to reduce free radical-mediated injury after ischemia and reperfusion.2,3 References/Citations1) Braughler et al...

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